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PGD2 Inhibitors
Ramatroban 3mg/ml , 60ml
SARMs S4 - 25mg/ml , 60ml
Clomiphene 50mg/ml , 60ML
Raloxifene 60mg/ml , 60ML
Tamoxifen (True Twenty) 30.4mg/ml , 60ML
Toremifene Citrate 30ML
Toremifene Citrate 60mg/ml , 60ML
Albuterol 6mg/ml, 60ML
Clenbuterol 200mcg/ml , 30ML
Clenbuterol 200mcg/ml , 30ML - (3 Pack)
Clenbuterol 200mcg/ml , 30ML - (5 pack)
Clenbuterol 200mcg/ml , 60ML
T3 100mcg/ml , 60ML
T4 400mcg/ml , 60ML
Anastrozole 1mg/ml , 30ML
Anastrozole 1mg/ml , 60ML
Exemestane 10mg/ml , 30ML
Exemestane 10mg/ml , 60ML
Letrozole 2.5mg/ml , 30ML
Letrozole 2.5mg/ml , 60ML
IGF-1 DES 1 3, 1200mcg
IGF-1 Lr3 (10 vials)
IGF-1 Lr3 (3 Vials)
IGF-1 Lr3, 1200mcg
IGF-1 Lr3, 1200mcg - (3 vials)
IGF-1 Lr3, 1200mcg - (5 vials)
IGF-1 RH, 1200mcg
IGF-2 Lr3 1200mcg
MGF (IGF-1Ec) 2000mcg
IGF-1 DES 1 3 KIT Receptor 1200mcg
IGF-1 Lr3 KIT Receptor 1200mcg
IGF-2 Lr3 Kit Receptor 1200mcg
Melanotan I 10mg
Melanotan II (10 vials) 100mg
Melanotan II 10mg
Melanotan II 30mg (3 Vials)
PT-141 (Bremalanotide) 10mg
GHRP-2 (4 Vials)
GHRP-2 (receptor) 5mg
GHRP-6 (receptor), 5mg
GHRP-6, (4 vials)
GnRH, 2000mcg
GRF [1 29] (3 vials)
GRF [1-29] 2000mcg
Hexarelin, 2000mcg
Ipamorelin, 2000mcg
Tesamorelin, 5 vial kit, 10mg
Ghrelex (D-Lys³ GHRP-6)
Oxytocin, 1200iu
Phospho DSIP 1000mcg
Thymosin Beta 4, 8mg (4 vial pack)
Dapoxetine HCL 30mg/ml , 30ml
Flibanserin 100mg /ml, 60ml
GW1516 - 5mg/ml , 30ml
Ketotifen Fumarate 2mg/ml , 60ml
Ostarine 25mg/ml , 60ml
Yohimbine HCL, 10mg/ml , 30ML
Cortexolone 17-Alpha Propionate 10mg / ml, 30ml
Dutasteride 0.5mg/ml , 60ml
Finasteride 5mg/ml , 30ml
Avanafil 50mg/ml , 60ml
Tadalafil 30mg/ml , 60ML
Meclofenoxate, 60g
Pramiracetam 30g
Cabergoline 0.5mg/ml , 30ml
Pramipexole Hydrochloride 1mg/ml , 60ml
ALT-711 (thiazolium chloride), 15g
Aminoguanidine HCL 75mg/ml , 60ml
Astragaloside IV 20mg/ml , 60ml
Cycloastragenol 5mg/ml , 60ml
Silibinin 100mg/ml , 60ml
Ursodeoxycholic Acid, 15g
Ursodeoxycholic Acid, 30g
Clen + Keto + Yohimbine
Tamox / Clom / Anast
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Raloxifene 60mg/ml , 60ML

Raloxifene 60mg/ml , 60ML



Raloxifen belongs to the class of compounds known as SERMs or selective estrogen receptor modulators.  SERMs decrease activity of estrogen and are therefore considered an “anti-estrogen” treatment.  However, SERMs do not act by decreasing serum estrogen or aromatase-mediated conversion, but rather through a blocking activity at the estrogen receptor on a cellular level.  In other words, raloxifen and its metabolites are active at the estrogen receptor but not as an estrogen-like stimulus (agonist).  Instead, they prevent estrogen from exerting its effects at the cellular level.  This (as well as other means of blocking estrogenic activity or reducing estrogen levels) creates a rise in testosterone in men because testosterone production is modulated partially via serum estrogen levels.


Raloxifen and its sister drug tamoxifen are typically used in treating estrogen-receptor dependent breast cancer in women[1].  Raloxifen may prove to have more diverse uses than tamoxifen for several reasons:


Selective estrogen receptor modulators (SERMs) or estrogen agonists/antagonists have shown promise in osteoporosis in that they have the potential to reduce the risk of fracture, and also reduce the risk of breast cancer. SERMs maybe classified according to their core structure, which is typically a variation of the 17 beta-estradiol template and subclassified according to the side chain at the helix 12 affector region. The best known are the triphenylethylenes such as tamoxifen, used in the management of breast cancer. However, the clinical application of this class of SERMs has been limited due to endometrial stimulation. A second class is the benzothiophenes such as raloxifene and arzoxifene, which have skeletal benefit with little, if any, uterine stimulation.[1]


In a study conducted by  Christodoulakis et al, “raloxifene users did not exhibit any difference with respect to sex steroids and HOMA-IR levels.”[2]


Raloxifen increased serum testosterone but reduced serum IGF-1 in a study performed by Duschek et al:


In aging men serum levels of testosterone and insulin-like growth factor-1 (IGF-1) decline, potential factors in the reduced muscle strength, abdominal obesity, sexual dysfunction and impaired general well being of aging. The partial oestrogen agonist and antagonist raloxifene increase serum testosterone levels in aging men, but the effect of raloxifene on serum IGF-1 levels in men is unknown. In this study the effects of raloxifene on IGF-1 levels and the associated increase in serum testosterone were compared to the effects of oral testosterone supplementation…. RESULTS: Compared to placebo raloxifene increased serum testosterone by 20% but it decreased serum IGF-1 levels by 24.5% (95% confidence interval (CI): -13.0 to -36.1%). No significant change in serum IGFBP-3 levels was found. The effect of raloxifene on serum IGF-1 has been observed with other oral oestrogens, and, therefore, is likely to be ascribed to the partial oestrogen agonist activity of raloxifene.[3]


According to Nordt et al, raloxifen may hold potential as an intervention in adolescent gynecomastia: “Newer treatment strategies, such as the antiestrogen raloxifene, have shown promising results; however, further studies are needed to determine long-term efficacy. As a result of the limited pharmaceutical treatment options, many more adolescents are seeking surgical intervention.[4]”


As the title of the study suggests, raloxifen is also a promising treatment for male osteoporosis:


Raloxifene has been shown to increase bone mineral density of the hip in men receiving androgen deprivation therapy for prostate cancer. Moreover, experimental data demonstrated dramatic increase in cell death in human prostate cancer cell lines after the treatment with raloxifene. All these observations suggest that SERMs may be useful for the prevention and treatment of osteoporosis not only in postmenopausal women but also in elderly men. However, our hypothesis should be tested in a proper designed clinical trial.[5]


Kastelan goes on to write that there are still issues of dose and duration to be assessed by further clinical study, as well as more markers of health and physical balance to be weighed against the benefits of raloxifen treatment.



[1] Silverman SL. New selective estrogen receptor modulators (SERMs) in development. Curr Osteoporos Rep. 2010 Sep;8(3):151-3.

[2] Christodoulakos G, Lambrinoudaki I, Panoulis C, Sioulas V, Rizos D, Caramalis G, Botsis D, Creatsas G. Serum androgen levels and insulin resistance in postmenopausal women: association with hormone therapy, tibolone and raloxifene.  Maturitas. 2005 Apr 11;50(4):321-30.

[3] Duschek EJ, Gooren LJ, Netelenbos C. Comparison of effects of the rise in serum testosterone by raloxifene and oral testosterone on serum insulin-like growth factor-1 and insulin-like growth factor binding protein-3.  Maturitas. 2005 Jul 16;51(3):286-93.

[4] Nordt CA, DiVasta AD.  Gynecomastia in adolescents. Curr Opin Pediatr. 2008 Aug;20(4):375-82.

[5] Kastelan D, Giljevic Z, Kraljevic I, Korsic M. Selective estrogen receptor modulators: A possible new treatment of osteoporosis in males. Med Hypotheses. 2006;67(5):1052-3.


*The latter article is intended for educational / informational purposes only. THIS PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

This product was added to our catalog on Monday 26 July, 2010.
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  AICAR KIT 100mg


  Cabergoline 0.5mg/ml , 30ml

Cabergoline 0.5mg/ml , 30ml

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